Monthly Archive for March, 2006

Nanoscaffolding to Regrow Nerves, Nanoscaffolding to Regrow Bone

From BBC Article “Nanotech helps blind hamsters see”:

An interesting article from the BBC examines what seems to be a way to produce self-assembling scaffolds for nerve regeneration: “The researchers injected the blind hamsters at the site of their injury with a solution containing synthetically made peptides – miniscule molecules measuring just five nanometres long. Once inside the hamster’s brain, the peptides spontaneously arranged into a scaffold-like criss-cross of nanofibres, which bridged the gap between the severed nerves. The scientists discovered that brain tissue in the hamsters knitted together across the molecular scaffold, while also preventing scar tissue from forming. Importantly, the newly formed brain tissue enabled the brain nerves to re-grow, restoring vision in the injured hamsters.”

And from a KurzweilAI we have “Researchers Grow Bone Cells on Carbon Nanotubes”:

Researchers at the University of California, Riverside have shown, for the first time, that bone cells can grow and proliferate on a scaffold of carbon nanotubes.

Because carbon nanotubes are not biodegradable, they behave like an inert matrix on which cells can proliferate and deposit new living material, which becomes functional, normal bone, according to the paper. They therefore hold promise in the treatment of bone defects in humans associated with the removal of tumors, trauma, and abnormal bone development and in dental implants.

Thanks to betterhumans

Nano Guided Missiles

University of Michigan physician and researcher James Baker has developed multipurpose nanoparticles precisely engineered to slip past barriers such as blood vessel walls, latch onto cancer cells, and trick the cells into engulfing them as if they were food. These Trojan particles flag the cells with a fluorescent dye and simultaneously destroy them with a drug.

The heart of Baker’s approach is a highly branched molecule called a dendrimer. Each dendrimer has more than a hundred molecular “hooks” on its surface. To five or six of these, Baker connects folic-acid molecules. Because folic acid is a vitamin, most cells in the body have proteins on their surfaces that bind to it. But many cancer cells have significantly more of these receptors than normal cells. Baker links an anticancer drug to other branches of the dendrimer; when cancer cells ingest the folic acid, they consume the deadly drugs as well.

technology review

Cyber-race

By Jerry Kang

Abstract


To date, most inquiries into race and cyberspace have focused on the “digital divide” – whether racial minorities have access to advanced computing-communication technologies. This paper asks a more fundamental question: Can cyberspace change the way that race functions in American society? Professor Jerry Kang starts his analysis with a social-cognitive account of American racial mechanics that centers the role of racial schemas. These schemas consist of racial categories, rules of racial mapping that place individuals into these categories, and racial meanings associated with each category. He argues that cyberspace can disrupt racial schemas because it alters the architecture of both identity presentation (enabling racial anonymity and pseudonymity) and social interaction (enabling increased interracial interactions). Thus, cyberspace presents society with three design options: abolition, which challenges racial mapping by promoting racial anonymity; integration, which reforms racial meanings by promoting interracial social interaction; and transmutation, which disrupts the very notion of fixed racial categories by promoting racial pseudonymity (or “cyber-passing”). After analyzing each option’s merits, Professor Kang concludes that society need not adopt a single, uniform design strategy for all of cyberspace. Instead, society can embrace a policy of digital diversification, which explicitly zones different cyber spaces according to different racial environments. For example, most market places could be zoned abolition, whereas most social spaces could be zoned integration. By encouraging a diversified policy portfolio, society can exploit synergies created by flexible zoning while avoiding policy lock-in. Although cyberspace is no panacea for the racial conflicts and inequality that persist, it offers new possibilities for furthering racial justice that should not be wasted.

Social Sciences Research Network

Aging Japan builds robot to look after elderly

TOKYO (AFP) – A Japanese-led research team said it had made a seeing, hearing and smelling robot that can carry human beings and is aimed at helping care for the country’s growing number of elderly.

Government-backed research institute Riken said the 158-centimeter (five-foot) RI-MAN humanoid can already carry a doll weighing 12 kilograms (26 pounds) and could be capable of bearing 70 kilograms within five years.

“We’re hoping that through future study it will eventually be able to care for elderly people or work in rehabilitation,” said Toshiharu Mukai, one of the research team leaders.

Covered by five millimeters (0.2 inches) soft silicone, RI-MAN is equipped with sensors that show it a body’s weight and position.

The 100-kilogram (220-pound) robot can also distinguish eight different kinds of smells, can tell which direction a voice is coming from and uses powers of sight to follow a human face.

“In the future, we would like to develop a capacity to detect a human’s health condition through his breath,” Mukai said.

Japan is bracing for a major increase in needs for elderly care due to a declining birth rate and a population that is among the world’s longest living.

The population declined in 2005 for the first time since World War II as more young people put off starting families.

Yahoo!

Supercomputer builds a virus

One of the world’s most powerful supercomputers has conjured a fleeting moment in the life of a virus. The researchers say the simulation is the first to capture a whole biological organism in such intricate molecular detail.

The simulation pushes today’s computing power to the limit. But it is only a first step. In future researchers hope that bigger, longer simulations will reveal details about how viruses invade cells and cause disease.

Klaus Schulten at the University of Illinois, Urbana, and his colleagues built a computer model of the satellite tobacco mosaic virus, a tiny spherical package of RNA.

Nature

Software Helps Develop Hunches

Eric Bonabeau, founder of Icosystem, has introduced “the hunch engine,” software designed to enhance and refine human intuition.

When the user starts the hunch engine he or she is presented with a seed—a starting point—and a set of mutations. The user selects mutations that look promising, and the application uses that selection to generate another set of mutations, continuing in that fashion until the user is satisfied with what they see.

One of its first applications is a filter for images that allows a naive user to improve digital photos without understanding complex tools like Adobe Photoshop, by choosing from mutations of the picture to make it better.

wired

Intelligent Intelligent Design

Surprisingly, Autodesk founder John Walker sides with intelligent design, but not by a deity—by post-Singularity intelligences creating a reality simulation: “What would we expect to see if we inhabited a simulation? Well, there would probably be a discrete time step and granularity in position fixed by the time and position resolution of the simulation—check, and check: the Planck time and distance appear to behave this way in our universe. There would probably be an absolute speed limit to constrain the extent we could directly explore and impose a locality constraint on propagating updates throughout the simulation—check: speed of light. There would be a limit on the extent of the universe we could observe—check: the Hubble radius is an absolute horizon we cannot penetrate, and the last scattering surface of the cosmic background radiation limits electromagnetic observation to a still smaller radius. There would be a limit on the accuracy of physical measurements due to the finite precision of the computation in the simulation—check: Heisenberg uncertainty principle—and, as in games, randomness would be used as a fudge when precision limits were hit—check: quantum mechanics.

New “Furry” Lobster Discovered

fuzzy
Divers have discovered a new crustacean in the South Pacific that resembles a lobster and is covered with what looks like silky, blond fur, French researchers said Tuesday.

Scientists said the animal, which they named Kiwa hirsuta, was so distinct from other species that they created a new family and genus for it.

A team of American-led divers found the animal in waters 2,300 meters (7,540 feet) deep at a site 1,500 kilometers (900 miles) south of Easter Island last year, according to Michel Segonzac of the French Institute for Sea Exploration.

CNN

Why Data Mining Won’t Stop Terror

In the post-9/11 world, there’s much focus on connecting the dots. Many believe data mining is the crystal ball that will enable us to uncover future terrorist plots. But even in the most wildly optimistic projections, data mining isn’t tenable for that purpose. We’re not trading privacy for security; we’re giving up privacy and getting no security in return.

Most people first learned about data mining in November 2002, when news broke about a massive government data mining program called Total Information Awareness. The basic idea was as audacious as it was repellent: suck up as much data as possible about everyone, sift through it with massive computers, and investigate patterns that might indicate terrorist plots.

Americans across the political spectrum denounced the program, and in September 2003, Congress eliminated its funding and closed its offices.

But TIA didn’t die. According to The National Journal, it just changed its name and moved inside the Defense Department.

Synthetic Validity

With the assembly line, Henry Ford created a unified production process that revolutionized the manufacturing industry. Now, a University of Calgary business professor has designed a unified selection process that promises to revolutionize the world of human resources.

Its technical name is ‘synthetic validity,’ and it has been the Holy Grail of business academics for the past 50 years. Once the system is implemented it’s expected to streamline hiring processes, save businesses many thousands of dollars, and contribute hundreds of billions of dollars annually to North American economies.

And what’s more, it can be applied to online dating.

sciencedaily

Bubble Fusion: Silencing the Hype

Taken together, the overall message from many people close to this work is that there is no longer any hope that this line of publications will yield a viable fusion energy source. For some this is almost liberating: those sticking with bubble fusion are freer than ever to explore other approaches to it, or to try other kinds of studies on acoustic chambers and the behaviour of collapsing bubbles. For others it is now the end of bubble fusion. There are other kinds of science to be done.

nature
a response from Taleyarkhan

Still Evolving, Human Genes Tell New Story

Providing the strongest evidence yet that humans are still evolving, researchers have detected some 700 regions of the human genome where genes appear to have been reshaped by natural selection, a principal force of evolution, within the last 5,000 to 15,000 years.

The genes that show this evolutionary change include some responsible for the senses of taste and smell, digestion, bone structure, skin color and brain function.

NYTimes

Tune in, turn on . . . evolve?

On the walls of dozens of caves in southern France and northern Spain lie some of the most majestic works of art ever painted. Drawn 25,000 to 40,000 years ago, the paintings have puzzled anthropologists since they were discovered more than four decades ago.

Where did this astonishing display of talent come from? Why did these prehistoric societies decide to paint these scenes in such remote locations? And what inspired them to paint the strange array of bisons, horses and therianthropes (part animal, part man)?

A scientific consensus of sorts has finally emerged on one of those questions: Although there are still dissenters, a majority of anthropologists now champion the theory that the paintings in Europe were the work of shamans, and in part the product of trance states, likely induced by psilocybin (the psychoactive ingredient in some species of mushrooms).

Similarly, South African anthropologist David Lewis-Williams maintains that the remarkable rock art of the San people of southern Africa, also painted at least 25,000 years ago, is the result of shamanic trances created by drumming and ritual ecstatic dancing.

In his new book, Supernatural: Meetings with the Ancient Teachers of Mankind, published by Random House, British writer Graham Hancock has taken Prof. Lewis-Williams’s research as a point of departure to posit a theory as fascinating as it is provocative: If it’s true that cave art derives from altered states of consciousness, then it constitutes a watershed moment in human history, marking the first visible encounter with the supernatural, the first expression of spiritual myth.

globeandmail.com