Archive for the 'Health/Bio-Tech' Category

Judge Nullifies Human Gene Patents

genes

A federal judge on Monday nullified patents associated with human genes known to detect early signs of breast and ovarian cancer.

It was the first time a federal court has invalidated a patent on genes. The American Civil Liberties Union, which brought the case, said the New York federal court decision “calls into question the validity of patents now held on approximately 2,000 genes.”

U.S. District Judge Robert Sweet agreed with the civil rights group that the patents were invalid because they covered the most basic element of every person’s individuality. “Products of nature do not constitute patentable subject matter absent a change that results in the creation of a fundamentally new product,” Sweet wrote in a 152-page opinion.

The lawsuit claimed the patents were so broad they barred scientists from examining and comparing the BRCA1 and BRCA2 genes at the center of the dispute. The patents issued more than a decade ago covered any new scientific methods of looking at these human genes that might be developed by others.

Augmented Reality in a Contact Lens

A contact lens with simple built-in electronics is already within reach; in fact, my students and I are already producing such devices in small numbers in my laboratory at the University of Washington, in Seattle. These lenses don’t give us the vision of an eagle or the benefit of running subtitles on our surroundings yet. But we have built a lens with one LED, which we’ve powered wirelessly with RF. What we’ve done so far barely hints at what will soon be possible with this technology.

Conventional contact lenses are polymers formed in specific shapes to correct faulty vision. To turn such a lens into a functional system, we integrate control circuits, communication circuits, and miniature antennas into the lens using custom-built optoelectronic components. Those components will eventually include hundreds of LEDs, which will form images in front of the eye, such as words, charts, and photographs. Much of the hardware is semitransparent so that wearers can navigate their surroundings without crashing into them or becoming disoriented. In all likelihood, a separate, portable device will relay displayable information to the lens’s control circuit, which will operate the optoelectronics in the lens.

French bread spiked with LSD in CIA experiment

In 1951, a quiet, picturesque village in southern France was suddenly and mysteriously struck down with mass insanity and hallucinations. At least five people died, dozens were interned in asylums and hundreds afflicted.

For decades it was assumed that the local bread had been unwittingly poisoned with a psychedelic mould. Now, however, an American investigative journalist has uncovered evidence suggesting the CIA peppered local food with the hallucinogenic drug LSD as part of a mind control experiment at the height of the Cold War.

[...]

On August 16, 1951, the inhabitants were suddenly racked with frightful hallucinations of terrifying beasts and fire.

One man tried to drown himself, screaming that his belly was being eaten by snakes. An 11-year-old tried to strangle his grandmother. Another man shouted: “I am a plane”, before jumping out of a second-floor window, breaking his legs. He then got up and carried on for 50 yards. Another saw his heart escaping through his feet and begged a doctor to put it back. Many were taken to the local asylum in strait jackets.

Telegraph.Co.Uk

‘Grow your own body parts’ could herald in the age of the active centenarian

British scientists are working on a system which should allow the elderly to buy body parts “off the shelf” and even regenerate their own damaged joints and hearts. As well as new harder wearing artificial hip and knee joints, their ultimate ambition is to fix up the body with customised replacement parts grown to order. They have already carried out human trials on heart valves which are still working four years after they were transplanted.

Telegraph.co.uk

Researchers use brain interface to post to Twitter

In early April, Adam Wilson posted a status update on the social networking Web site Twitter — just by thinking about it.

Just 23 characters long, his message, "using EEG to send tweet," demonstrates a natural, manageable way in which "locked-in" patients can couple brain-computer interface technologies with modern communication tools.

EurekAlert!

View and download a video of Wilson using the brain-computer interface to post to Twitter at http://nitrolab.engr.wisc.edu/media/P3Twitter.mov

Scorpion venom with nanoparticles slows spread of brain cancer

By combining nanoparticles with a scorpion venom compound already being investigated for treating brain cancer, University of Washington researchersimage found they could cut the spread of cancerous cells by 98 percent, compared to 45 percent for the scorpion venom alone. 

"People talk about the treatment being more effective with nanoparticles but they don’t know how much, maybe 5 percent or 10 percent," said Miqin Zhang, professor of materials science and engineering. "This was quite a surprise to us." She is lead author of a study recently published in the journal Small.

EurekAlert!

Zebrafish Regenerative Ability May Help Humans

Biologists have discovered a molecular circuit breaker that controls a zebrafish’s remarkable ability to regrow missing fins, according to a new study from Duke University Medical Center.

Tiny wonders of the aquarium world, zebrafish can regenerate organs and tissues, including hearts, eye parts and fins. When a fin is lost, the fish regenerates a perfect copy in two weeks by orchestrating the growth of many tissue types, including bone, nerves, blood vessels, connective tissue and skin.

Scientists hope that understanding how zebrafish repair themselves will lead to new treatments for human conditions caused by damaged tissue, such as heart failure, diabetes and spinal cord injuries.

Science Blog

Next plague likeliest to emerge from poor tropical countries

Scores of infectious diseases have emerged to threaten humans in the past decades as viruses leap the species barrier from wild animals and bacteria mutate into antibiotic-resistant strains, scientists reported on Wednesday.

Presenting the first-ever map of “hotspots” of new infectious diseases, they predict that the next pandemic is likeliest to come out of poor tropical countries, where burgeoning human populations come into contact with wildlife.

A three-year investigation led by four major institutions tracked 335 incidents since 1940 when a new infectious disease emerged.

The category includes HIV/AIDS, which has slain or infected more than 65 million people around the world, and outbreaks of severe acute respiratory syndrome (SARS) and H5N1 bird flu, which have cost tens of billions of dollars to contain.

Yahoo via Posthuman Blues

Horizon: Britain’s Most Dangerous Drug

New Bone Created In Minimally Invasive Procedure

A new technique that combines bone marrow removal and injection of a hormone helps promote rapid formation of new bone at targeted locations in the body, it was reported by Yale School of Medicine recently in Tissue Engineering.

“This could radically change the way patients are currently treated for weakened or fractured hips, vertebrae and acute traumatic long bone fractures,” said senior author Agnès Vignery, associate professor of orthopedics.

She said currently available treatment requires surgery and artificial materials and often results in imperfect outcomes. “The ideal approach would be to create new bone where it is needed and at a faster rate,” Vignery said.

Science Daily

Pet dog to be cloned by Korean biotech

A South Korean biotech company has announced it will, for the first time ever, commercially clone a pet dog, according to reports coming out of the country.

RNL Bio said last week that it received an order from Californian Bernann McKunney, to clone her deceased pet pitbull, Booger, to the tune of $150,000. Booger died in 2005, but not before McKinney had tissue from his ear preserved.

The Korean company told the BBC that the cloning will take place at Seoul National University (SNU), where the first dog, Afghan hound Snuppy, was successfully cloned as a proof of concept in 2005. The SNU team that will recreate Booger is headed by Lee Byeong-chun, who was a colleague of Hwang Woo-suk, the disgraced Korean stem cell scientist who admitted fabricating data on human embryonic stem cell lines in 2006. Hwang’s dog cloning work, however, was determined to be legitimate, and the SNU team went on, after Hwang’s departure from the university, to successfully clone wolves.

The Scientist

Breaking the Drug Taboo: Group of Traumatized Veterans Get Ecstasy Treatment

An experimental study that treats PTSD veterans with the drug MDMA could make life after war a lot more livable.

“We need to be positioning ourselves now to provide the assistance that our veterans need,” said House Committee on Veterans’ Affairs chairman Bob Filner (D-CA) during a hearing, called “Stopping Suicides: Examining the Mental Health Challenges Facing the Department of Veterans Affairs,” held in December 2007. “Not only for those brave men and women who are returning home from Iraq and Afghanistan, but also for our veterans from previous conflicts. We cannot afford to put this issue off.”

Filner’s choice of words is instructive, as are his sentiments: With upwards of 25 million veterans in the United States, not counting those overseas in the morally murky theater of Iraq and Afghanistan who may return home sometime after the 2008 presidential election, that’s a lot of assistance and funding needed to head off what he called a “rate of veteran suicide [that] has reached epidemic proportions,” to the point that it has doubled the suicide rate of civilians. Safeguards already put into place have failed, for a variety of reasons, and given the severity of the mental and physical problems carried by returning soldiers, some daring out-of-the-box thinking is not only desperately needed, but required.

Enter the Multidisciplinary Association for Psychedelic Studies (MAPS), and its currently funded trials using 3,4-methylenedioxy-N-methamphetamine—otherwise known as MDMA, or ecstasy—to treat post-traumatic stress disorder (PTSD). Although the U.S. Army had carried out lethal dose studies of MDMA back in the 1950s, work which was not classified until the close of the 1960s, it was only centered on animals and was mixed in with a variety of other compounds. At the closure of that research, MDMA languished in clinical obscurity until its rise as a club drug in the ‘80s and ‘90s brought it the kind of attention that dooms better drugs to Schedule I classifications—that is, illegality—and lesser drugs to approval by the Food and Drug Administration (FDA). But MAPS founder and president Rick Doblin became aware of MDMA in 1982, and since then has been convinced of its therapeutic uses. Accordingly, his organization has coordinated and/or funded recent studies into MDMA treatment of PTSD and has its eyes set on a higher goal.

“We’re looking to make MDMA into a prescription medication in the United States, United Kingdom and elsewhere,” he explained by phone.

Entheology

Scientists breed world’s first mentally ill mouse

Scientists have created the world’s first schizophrenic mice in an attempt to gain a better understanding of the illness.

It is believed to be the first time an animal has been genetically engineered to have a mental illness. Until now they have been bred only for research into physical conditions such as heart disease. It will allow researchers to study the disease and develop treatments using a limitless supply of laboratory animals.

Times Online via TechnoOccult

With Mini in vivo Robots, Anyone Can do Surgery

miniinvivorobots.png

By attaching a millimeter-sized camera robot to a tether, scientists have designed a way to allow individuals with non-medical backgrounds to perform minimally invasive surgery in almost any location. Unlike room-size and expensive surgical robots, mini in vivo robots are inexpensive and mobile enough to support emergency surgeries almost anywhere, from the battlefield to outer space.

The University of Nebraska researchers hope that the inexpensive version of the da Vinci surgical robot system will make the advantages of robotic-assisted surgery more widely available, and open the doors for telesurgeries that were previously impossible. In a recent study, the team evaluated the ease of use and time required to perform simple abdominal surgeries with the in vivo camera robots. Their results are published in a recent issue of IEEE Transactions on Information Technology in Biomedicine.

“A new area of surgical robotics focuses on placing robots entirely inside the patient,” wrote Mark Rentschler et al. in their study. “In vivo robots are small, inexpensive, and easily transported, making it more likely that this technology can be more widely adopted. . . . The use of these robots can potentially reduce patient trauma in traditional medical centers, while the size of the robots makes them ideal for transportation to and use in remote or harsh environments.”

PhysOrg

Cruising the Amazon

Life is everywhere in the upper Amazon wilderness. Life that creeps, life that crawls, life that slithers, sprouts, burrows, scurries and slinks—and dies. The dank odors of alternating rot and genesis rise from the mulching forest floor. My Deet-fortified insect spray battles swarms of blood-mad mosquitoes to a draw. The air is fat with syrupy humidity, and I am sweating like an icicle in the sun.

Nature is on fast-forward here. Trees—palms, laurels, kapoks, mahoganies, bamboos, acacias, figs, balsas, cedars—jostle each other in the search for a share of the sunlight; they grow to enormous heights and spread their foliage like a green umbrella at the top. Lianas, tropical climbing plants, wind themselves like boa constrictors around the tree trunks and arch themselves in great loops as they, too, struggle upward for a glimpse of light. The trees become parasites, and giant orchids seed themselves in branches 60 feet from the ground. The general effect is of a an impenetrable fecund, living wall.

Amid this vast assortment of life, creatures use stunts and flim-flam to befuddle or repel predators, lure prey, seduce mates and gobble food. Caterpillars masquerade as snakes, plants imitate the smell of rotting meat to attract flies as pollinators, and trees rely on fish to distribute their seeds when the rivers flood.

It’s a jungle out here.

Chicago Tribune